A new study conducted by Sweden-based Lund University researchers has discovered that type 2 diabetes patients can manage their blood sugar with broccoli sprout extract.
The researchers said the findings could offer a much needed alternative to address type 2 diabetes, which has become a worldwide epidemic. For the full scoop on these new findings, keep reading...
Most type 2 diabetes patients can’t take first-line therapy metformin due to kidney damage risks...
To arrive at the conclusion that broccoli extract can help type 2 diabetes
keep their blood sugar
steady, the researchers took a computational approach to identify the compounds that might counter the disease-associated gene expression changes associated with type 2 diabetes.
Statistics reveal that type 2 diabetes affects more than 300 million people around the world and that as many as 15% of those patients can’t take the first-line therapy metformin because of kidney damage risks.
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Swedish researchers find that broccoli extract can help type 2 diabetes patients manage their blood sugar
The researchers developed a signature for type 2 diabetes based on 50 genes. They then used publically available expression datasets to screen 3,852 compounds for drugs that potentially reverse type 2 diabetes.
Their research determined that sulforaphane – a naturally occurring compound found in cruciferous vegetables such as broccoli – was successful in decreasing glucose production by liver cells growing in culture while shifting liver gene expression from a diseased state in rats with diabetes.
To test the affects of sulforaphane on humans with type 2 diabetes, the researchers gave concentrated broccoli sprout extracts to 97 patients in a 12-week randomised placebo-controlled trial. They found that obese patients shows significantly reduced fasting blood glucose levels compared with those in the control group.
The researchers concluded that developing gene signatures to explore large public repositories of gene expression data could be a valuable strategy to rapidly identify compounds that fight type 2 diabetes.
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