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This is how colon cancer is different in people under the age of 50

by , 04 June 2015

A new study has found that colon cancer is genetically different in older and younger patients, and young adults might require new treatments.

Which raises one question: Why?

According to the study, conducted by researchers at the University of Colorado Cancer Center in the US, colon cancer is much more aggressive in patients younger than 50 than in older people.

To find out more, keep reading…

Colon cancer can be much more serious in younger people

For the study, researchers compared the genetics of five colon cancer tumours from younger patients (half of them younger than 31) and six tumours from older patients (half older than 73).
Study author Dr Christopher Lieu reports: “We saw differences in two important gene-signalling pathways – PPAR and IGR1R – which are involved in regulating cell development, metabolism and growth.”
Dr Lieu explains that changes in signalling pathways correlate with several different types of cancer, including cancer of the colon.
The team of researchers also found that pathways responsible for metabolising drugs enriched tumours in younger patients.
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How chemotherapy affects young and old colon cancer patients differently 

“Chemotherapies challenge cancer cells and younger people may metabolise these chemotherapies differently than older patients. This may explain why our traditional chemotherapy treatments may be less effective for younger patients with metastatic colorectal cancer,” study author Dr Todd Pitts said in a news release.
Researchers say they’re planning a larger study to confirm and explain their findings.
“If I were to shoot for the stars, I would say that our end goal is to be able to offer better treatments for this population of young colorectal cancer patients that seems to be at higher risk from the disease,” Dr Lieu says.
To find out who’s at double the risk of developing colon cancer, read this.
Editor’s Note: Are you ready to find out the root of all cancers? In the April 2015 issue of the Natural Health Dossier, we let you in on this secret. To access this issue and others, join Natural Health Dossier today. It’s quick and easy!

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